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在线翻译:
szdaily -> Speak Shenzhen -> 
Men have a biological clock too
    2019-05-20  08:53    Shenzhen Daily

男人也有生殖生物钟

It’s usually women who are burdened with the biological clock concept, but new research suggests men may also have a time limit on having children.

According to a new study published in the journal Maturitas, men should consider banking their sperm before reaching “advanced paternal age,” which has been variably defined as above 35 or 45 in medical fields.

This is because men older than this may experience decreased fertility, the study states, and put their female partners at higher risk of a number of pregnancy and birthing complications, such as gestational diabetes, pre-eclampsia and preterm birth.

Additionally, infants born to older fathers may also be at higher risk of a number of conditions, such as congenital heart disease, newborn seizures and low birth weight.

The study also found that some of these children were more likely to develop certain cancers and cognitive disorders, such as autism.

The study reviewed 40 years worth of research to reach its conclusions on the effects paternal age had on fertility, pregnancy and health of children.

Lead author Gloria Bachmann, director of the Women’s Health Institute at Rutgers Robert Wood Johnson Medical School, commented, “While it is widely accepted that physiological changes that occur in women after 35 can affect conception, pregnancy and the health of the child, most men do not realize their advanced age can have a similar impact.”

“In addition to advancing paternal age being associated with an increased risk of male infertility, there appears to be other adverse changes that may occur to the sperm with aging.

“For example, just as people lose muscle strength, flexibility and endurance with age, in men, sperm also tend to lose ‘fitness’ over the life cycle.”

As for the reasons behind this, Bachmann suspected it’s down to the natural decline in testosterone levels man experience as they age, in addition to a reduction in semen quality. When men age they become more predisposed to sperm degradation, the study found, which, during conception, can lead to heredity mutations in the DNA cells of the offspring that prompt a number of disorders.

Some studies have shown that the risk of autism starts to increase when the father is 30, plateaus after 40 and then increases again at 50.

Words to Learn 相关词汇

【有...倾向的】yǒu ...qīngxiàng de

predisposed made susceptible

【进入平台期】jìnrù píngtáiqī

plateau reach a stable level

人们通常认为女性才会被生殖生物钟所累,但新研究指出,男性也有生育年龄极限。

根据发表在《欧洲更年期杂志》期刊上的新研究,男性应考虑在到达“生殖高龄”前冷冻精子,医学界将男性生殖高龄定义为35岁或45岁以上。

研究指出,这是因为超出生殖高龄的男性生殖能力会下降,并会增加女性伴侣孕期和分娩并发症的风险,比如妊娠糖尿病、先兆子痫和早产。

此外,高龄父亲所育的婴儿患上先天性心脏病、新生儿癫痫和出生体重过低等多种疾病的风险也更高。

研究还发现,父亲年龄偏大的一些孩子更容易患上某些癌症和自闭症等认知障碍疾病。

该研究回顾了40年间的研究成果,最后总结出了父亲的年龄对生殖能力、怀孕和子女健康的影响。

研究报告的首席作者、罗格斯大学罗伯特伍德约翰逊医学院的女性健康研究所所长格洛丽亚●巴赫曼评论说:“尽管人们普遍认为女性在35岁后的生理变化会影响受孕、怀孕和胎儿健康,但多数男性没有意识到自己年龄偏大也会产生相似的影响。”

“父亲年龄过大不仅和男性不育风险增加有关,男性变老似乎还会对精子产生其他负面影响。”

“例如,正如人们变老后肌肉会失去力量、柔韧性和耐力一样,精子也会在这一过程中变得越来越虚弱。”

至于这一现象背后的原因,巴赫曼怀疑是因为男性变老时睾酮水平随之自然下降,与此同时精液质量也降低了。

研究发现,当男性变老时,精子退化的倾向进一步加强。精子退化会在受孕时导致后代的DNA细胞发生遗传突变,从而引发多种病症。

一些研究显示,男性年过三十后所育子女的自闭症风险开始增加,年过四十后,这一风险趋于平稳,年逾五十后自闭症风险又继续攀升。

(Chinadaily.com.cn)

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