LYNN SHELTON, an independent filmmaker who directed “Humpday” and “Little Fires Everywhere,” has died. She was 54.

Shelton’s publicist, Adam Kersh, said in a statement Saturday that she died Friday in Los Angeles from an unidentified blood disorder.

Shelton had become the leading voice of the new American independent cinema movement. She caused waves with her low-budget films, then made splashes through her work on television including “Mad Men,” “Fresh Off the Boat,” “The Mindy Project” and “GLOW.”

Her films were known for naturalistic acting, often-improvised dialogue and a focus on interpersonal relationships.

She directed four episodes of the Hulu miniseries “Little Fires Everywhere,” starring Reese Witherspoon and Kerry Washington.

“We made so many things together,” said Mark Duplass on Twitter. He was a frequent collaborator with Shelton starring in her 2009 film “Humpday,” which was a depiction of male sexuality through a female lens. The actor said he lost a “dear friend” and admired her creativity.

“I wish we had made more,” Duplass said. “Her boundless creative energy and infectious spirit were unrivaled.”

Shelton began her filmmaking career in her mid-30s after initially being an aspiring actor and photographer. She went on to write and direct eight feature films in the span of 14 years.

The statement said she had an “infectious laugh, was full of life and had an esprit de corps that touched many.”(SD-Agencies)