Time: 8:30-9:15 a.m., July 25

Location: Hall 4, 1F, Shenzhen Convention and Exhibition CenterGenetic and epigenetic variation can impact gene transcription and phenotypic diversity and may thus contribute to adaptation. Geographic origin is a major predictor of global DNA methylation levels and altered gene expression caused by epialleles. Analysis of the cistromes and epicistromes of these 1,001 accessions revealed significant association between transcription factor binding (TF) sites, methylation and nucleotide variation and co-expression modules. To more directly interrogate the effects of genetic and epigenetic variation on TF binding, we developed a high-throughput TF binding site discovery method and defined the Arabidopsis cistrome by resolving motifs and peaks for a large number of TFs. Joseph R. Ecker

Joseph Ecker is an American plant biologist and molecular biologist. He is a professor of Plant Molecular and Cellular Biology Laboratory and director of the Genomic Analysis Laboratory at the Salk Institute for Biological Studies. He is also an investigator of the Howard Hughes Medical Institute.