MANUEL LANZINI fired West Ham to its first win at Old Trafford since 2007 as underwhelming Manchester United bowed out of the League Cup in the third round while Chelsea and Tottenham survived penalty shootouts to advance Wednesday.

The Hammers suffered a gut-wrenching 2-1 defeat against United in the Premier League on Sunday when David De Gea saved Mark Noble’s stoppage-time penalty after Jesse Lingard’s late winner.

But David Moyes’ men got a measure of revenge three days later as Lanzini’s first half goal dumped United out in the third round.

Solskjaer made 11 changes and Moyes opted for 10 alterations, with West Ham’s understudies making the most of their moment in the spotlight.

Ryan Fredericks ghosted past Alex Telles and cut back for Lanzini to sweep past United goalkeeper Dean Henderson in the ninth minute.

That was enough for Moyes to secure a first win over United since they sacked the Scot after less than a season in charge in 2014.

At Stamford Bridge, Chelsea won 4-3 on penalties after a 1-1 draw against Aston Villa.

German forward Timo Werner headed Chelsea into the lead in the 54th minute, finishing off Reece James’ cross for his first goal in 11 games.

With Villa fan Prince William watching from the stands, 19-year-old striker Cameron Archer equalized in the 64th minute with a close-range header from Matty Cash’s cross.

James scored Chelsea’s winning penalty in the shoot-out after Ashley Young and Marvelous Nakamba missed for Villa.

Harry Kane ended his goal drought as Tottenham boss Nuno Espirito Santo knocked out his former club Wolves 3-2 on penalties after a 2-2 draw at Molineux.

Tanguy Ndombele gave Tottenham a 14th-minute lead when he charged down Conor Coady’s clearance and shot past John Ruddy.

Kane, without a goal in his four previous games, increased Tottenham’s advantage after 23 minutes.

Dele Alli’s perfect pass sent Kane clear and the England captain found the bottom corner.

Leander Dendoncker pulled one back for Wolves seven minutes before the break when he headed in Rayan Ait-Nouri’s corner.

Daniel Podence levelled 13 minutes into the second half from Dendoncker’s pass.

In the shootout, Dendoncker, Ruben Neves and Coady all missed for Wolves.

Arsenal eased to a 3-0 win against third-tier AFC Wimbledon at the Emirates Stadium.(SD-Agencies)