A: We really don’t want to let you go. You do so much for the company that I don’t see how anyone could fill your shoes.

B: I appreciate your saying that. I don’t want to leave the company but I really need to return to my hometown to take care of my family.

Note: This is a figurative expression, which means “to take the place of some other person and do that person’s work satisfactorily,” as if you were wearing the other person’s shoes. For example: John expects his son to fill his shoes at the store.