DIRECTOR Martin Scorsese and actor Leonardo DiCaprio are to team up for a big screen adaptation of Erik Larson’s 2003 book “The Devil in the White City.”

    DiCaprio is expected to play serial killer Dr. HH Holmes, who used the 1893 World’s Fair in Chicago to lure his victims to their deaths.

    Holmes claimed to have killed 27 people — although some later estimates put his death toll at nearer 200.

    It will be the sixth time DiCaprio has worked with Scorsese. Their previous films include “The Wolf of Wall Street,” “The Departed” and “Gangs of New York.”

    DiCaprio reportedly bought the film rights to “The Devil in the White City” in 2010. It tells the story of Dr. Holmes, who converted a large building in Chicago into what became known as a “murder castle.”

    It had a padded room with a gas pipe to asphyxiate victims, a chute for dispatching bodies to the cellar and, in the cellar, a hidden butcher’s table and oven where investigators found the remains of women’s clothing.

    The screenplay will be written by Billy Ray, who scripted “Captain Phillips” and “The Hunger Games.”(SD-Agencies) Martin Scorsese (L) and Leonardo DiCaprio.